E. ADVANCED SPECIFIC COURSES

 

The requirement of the advanced specific Courses must reach 6 credits.

E1. Special Topics in Analytical Chemistry (3 credit-hours)

A course of lectures and seminars devoted to modern methods in analytical chemistry. Two of the following topics will be considered each semester: instrumental methods in spectroscopic analysis; scattering and diffraction methods; electroanalytical and polarographic techniques, chromatography; separation and purification methods; tracer methods. Readings from the current literature will be the basis of both lectures and seminars.

E2. Enzyme Reaction Mechanisms (3 credit-hours)

The mechanism of enzyme action will be examined with emphasis on the following topics: three dimensional structure of enzymes; chemical catalysis; methods of determining enzyme mechanisms; stereochemistry of enzymatic reactions; detection of intermediates; affinity labels and suicide inhibitors; transition state analogs; energy relationships, evolutionarily "perfect" enzymes; genetic engineering and enzymes; use of binding energy in catalysis. Instruction will be in both lecture and seminar format, with emphasis on recent literature.

E3. Special Topics in Biochemistry (3 credit-hours)

Series of seminars dealing with topics of current research interest in the field of Biochemistry. A single area, in which advances of major significance have been made, may be chosen.

E4. Special Topics in Chemistry (3 credit-hours)

A series of lectures and seminars dealing with recent or current important developments in chemistry. A single area, in which advances of major significance have been made, will be selected, or a given term, e.g. physical, organic, or inorganic chemistry, will be focused upon.

E5. Proteomics (3 credit-hours)

“Proteomics” is derived from the word ‘proteome’ that refers to the proteins encoded by an entire genome. The last decade has been called the “Decade of Genomics”, and the first decade of the new millennium has been named the “Decade of Proteomics”. The sequencing of entire genomes, including the human genome, is resulting in the identification of a huge number of novel proteins whose functions are unknown. The major challenge of biomedical research during the next decade will include characterization of the properties and biological functions of about 100,000 different human proteins, and how these are involved in human disease. Beside the human proteins, hundreds of thousands of proteins from other eukaryotic and procaryotic species need to be characterised. This huge work will require multi-methodological efforts requiring the input of methods of genetics, developmental biology, cell and molecular biology, physiology, protein chemistry, as well as structural biology and molecular modelling. 

Course programme

  1. Introduction to Proteomics 
  2. Bioinformatics – from Gene to Protein Function
  3. Analysis of Proteome
  4. Enzyme Catalysis
  5. Protein Factories
  6. Analysis of Proteomes 
  7. From Protein to Disease and Vice Versa
  8. Protein Structure

E6. Developmental Biology and Cellular Signalling (3 credit-hours)

This programme offers a postgraduate training programme curriculum in the fields of Developmental Biology and Cellular Signalling. 

Research in these areas encompasses:

  1. Cellular and molecular biology
  2. Development of various organ systems
  3. Stem cell biology
  4. Haematology and immunology
  5. Molecular and clinical endocrinology
  6. Genetics, paediatrics
  7. Obstetrics and gynaecology. 

E7. Inflammation and Allergy (3 credit-hours)

The main task is to provide coordinate PhD course of relevance to postgraduate students that are enrolled in the PhD programme within Molecular Medicine. 

The course includes:

  1. Balancing inhibitory and activating receptors during immune responses
  2. Cytokines in inflammation
  3. Manipulation of Humoral Immunity

E8. Cellular and Molecular Immunology (3 credit-hours)

The course covers cells and tissues of the immune system, lymphocyte development, the structure and function of antigen receptors, the cell biology of antigen processing and presentation, including molecular structure and assembly of MHC molecules, the biology of cytokines, leukocyte-endothelial interactions, and the pathogenesis of immunologically mediated diseases. The course is structured as a series of lectures and tutorials in which clinical cases are discussed with faculty tutors.

E9. Cellular and Molecular Developmental Biology (3 credit-hours)

This course will explore current cellular and molecular concepts in developmental biology. Topics covered will include regulation of development by transcription factors and growth factors, epithelial-mesenchymal interactions, cell cycle, cell migrational cues, homeobox genes, pattern formation, angiogenesis, and DNA repair.

E10. Introductory Course in Tumor Biology/Oncology (3 credit-hours)

The objective is to give students an opportunity to learn more about the theoretical background as well as some practical skills in the area of Oncology/Tumor Biology. 

The course includes:

  1. An introduction to tumor pathogenesis
  2. Causes of cancer
  3. Molecular cell- and tumor biology
  4. Tumor immunology
  5. Cancer genetics 

The course will be in the form of lectures, seminars, and literature studies. The course touches upon up-to-date results from the frontiers of cancer research and a presentation of the objectives within these research areas. Based on the given objectives, the students are encouraged to, under supervision, independently search and evaluate the available literature and to come with suggestions of experimental setups. The main part of the course is devoted to conducting an individual project, focusing on the objectives and methodology of a specific subject area