PGD TECHNIQUES USED TO ANALYZE GENETIC MATERIAL FROM THE EMBRYO

  • Fluorescence in situ hybridization analysis (FISH) – Fluorescent DNA probes determine genetic abnormalities. It is used for sex determination in diseases linked to gender, as well as for numerical and structural chromosomal abnormalities.
  • Polymerase chain reaction (PCR) – Detects the mutation of a single gene, such as sickle cell and thalassemia disorders.
  • Haplotyping – DNA fingerprinting identifies chromosomes carrying affected genes.
  • DNA Chip, or Gene Chip - Allows the DNA of the embryo to be compared to over 20,000 different genetic mutations.

 

  • TITLE : FISH signals from chromosomes in a blastomere
  • TITLE : FISH signals from chromosomes in a blastomere
  • TITLE : Polymerase chain reaction (PCR)
  • TITLE : Haplotyping
  • TITLE : DNA Chip
  • TITLE : DNA Chip