MORPHOLOGICALLY SELECTED INTRACYTOPLASMIC SPERM INJECTION (IMSI)

High magnification ICSI or IMSI is used to fine-tune the ICSI process. It allows examination of sperm morphology under an extremely high-magnification (X6000) prior to injecting it into the egg.

IMSI displays chromatin compaction defects, which appear as holes inside the nucleus called 'vacuoles', allowing selection of sperm without defects or those with fewer vacuoles, thus increasing rates of implantation/pregnancy, and reducing miscarriage rates.

Patients with severe oligoasthenoteratozoospermia can benefit from IMSI.